Biotherapeutic effects of probiotic bacteria on candidiasis in immunodeficient mice.
The prolonged survival of mice, decreased severity of mucosal and systemic candidiasis, modulation of immune responses, decreased number of C. albicans in the alimentary tract, and reduced numbers of orogastric infections demonstrated not only that probiotic bacteria have biotherapeutic potential for prophylaxis against and therapy of this fungal disease but also that probiotic bacteria protect mice from candidiasis by a variety of immunologic and nonimmunologic mechanisms in this model.
Wagner, R. Doug, et al. (October 1997). Biotherapeutic effects of probiotic bacteria on candidiasis in immunodeficient mice.