Five Lesser-Known Signs of Hypothyroidism

January 19, 2022

Signs of Hypothyroidism

When you think of low thyroid function, or hypothyroidism, weight gain probably comes to mind first. This is probably the most common and well known symptom of hypothyroidism, but there are some lesser known signs and symptoms of hypothyroidism that some doctors, and even fewer patients, are aware of, but can help lead to the correct diagnosis.

1. Loss of the Outer Edge of the Eyebrows

It is a well-established fact that endocrine disorders such as hypothyroidism can cause hair loss. In thyroid dysfunction, other than scalp hair, hair on other parts of the body may also be affected, such as eyebrows and body hair.(1) You may notice a heavier-than-normal loss of hair from the head. Even body hair, including underarm and pubic hair, may shed or thin. This sort of hair loss can be due to a thyroid problem, but it can also show up with other hormonal imbalances, illnesses, age, and due to genetics and heredity.

One type of hair loss is considered unique to hypothyroidism. It is the loss of the hair in the outer edge of the eyebrows. This is a characteristic sign of hypothyroidism, and is not linked to other diseases, and so many physicians consider it a very important clinical sign.

If you have any unexplained hair loss, and especially, if you have loss of hair from the outer edge of your eyebrows, it’s time for a thorough thyroid evaluation from a knowledgeable doctor.

2. Elevated Cholesterol 

Many people have elevated cholesterol levels, and doctors are becoming more aggressive about recommending treatment. Often for borderline-high levels, doctors recommend diet and exercise to get the numbers down and back into balance. If that doesn’t work, or if the numbers are especially high, doctors may recommend cholesterol-lowering drugs such as Lipitor, however we caution against using these statin drugs. Watch this podcast with Dr. Hotze as he discusses the dangers of statin drugs.

Thyroid disorders are known to influence lipid metabolism and are common in patients with elevated cholesterol. Hypothyroidism has an adverse effect on the serum lipid profile that may predispose to the development of atherosclerotic disease. Thyroid substitution therapy is beneficial for patients with hypothyroidism.(2)

If you have high cholesterol, you should always have a thorough, comprehensive thyroid evaluation for hypothyroidism.

3. Constipation

It’s one of those topics we often don’t want to discuss, but persistent or chronic constipation can be a sign of an underactive thyroid. Because the thyroid regulates metabolism, the metabolic slowdown of hypothyroidism also slows down the digestive system, and food moves more slowly through digestion and elimination, frequently resulting in chronic constipation. Research shows that hypothyroidism prominently reduces esophageal and gastric motor activity and can cause gastrointestinal dysfunction (3) and that hypothyroidism contributes to chronic constipation. (4,5)

Often, common remedies, such as increasing water intake, fruits like dried prunes or prune juice, and upping the fiber intake, are tried with no results. Over-the-counter, herbal and prescription drugs may also fail to resolve the problem.

If you are experiencing chronic constipation, you should always be exhaustively evaluated for an underactive thyroid.

4. Loss of Sex Drive

Many women consider loss of sex drive as an unavoidable part of getting older, but it doesn’t have to be that way. Low, or no,  sex drive may actually be a sign of undiagnosed, untreated hypothyroidism. Research demonstrates that hypothyroidism can cause decreased sexual desire. (6) If you have a problem with your libido, any medical workup your doctor does to evaluate you should also include a complete thyroid examination, to rule out low thyroid as a potential cause.

5. Depression

According to the National Institute of Mental Health, in 2015 an estimated 16.1 million adults in the United States had at least one major depressive episode.   Depression and mood changes can be a symptom of untreated low thyroid. Study results show a significant association of hypothyroidism with psychiatric disorders – an increased frequency of depression and anxiety symptoms.(7)

Patients with thyroid disorders are more prone to develop depressive symptoms. Both excess and insufficient thyroid hormones can cause mood abnormalities, including depression, that is generally reversible with adequate thyroid treatment. Furthermore, thyroid hormones are reported by many to be an effective treatment for depression. (8)  And unfortunately, some of the millions of people diagnosed and treated for depression and mood disorders are actually suffering from undiagnosed hypothyroidism.

There is no blood test for depression, so diagnosis is made based on a discussion of the symptoms. But thyroid disease diagnosis requires evaluation and testing, and so with today’s conventional doctors only spending a few minutes with you, mood-related symptoms are quickly attributed to depression, and a prescription written for antidepressants or anti-anxiety medications, rather than a more time-intensive thyroid evaluation. Please don’t stop taking your antidepressant or anti-anxiety medication since it can have dangerous side effects. You must work with your doctor to slowly and safely wean off any medication.

It’s essential that everyone diagnosed with depression or other mood disorders be fully evaluated as early as possible to rule out any underlying thyroid imbalances.

We Can Help

At the Hotze Health & Wellness Center, we help give people their lives back, naturally. If you are struggling with symptoms of hypothyroidism or hormone decline and imbalance that occurs in women, as well as men, and take our symptom checker to help find out what’s going on. Contact us at 281-698-8698 for a complimentary wellness consultation with a Wellness Consultant. It will be our privilege to serve you.

Related Content
Getting to the Root Cause of Hair Loss
Hidden Danger of Cholesterol-Lowering Drugs
Why Your Doc Misses the Hypothyroidism Diagnosis

1. A Descriptive Study of Alopecia Patterns and their Relation to Thyroid Dysfunction
2. Dyslipidemia in Patients With Thyroid Disorders
3. Does Hypothyroidism Affect Gastrointestinal Motility?
4. Chronic Constipation: An Evidence-Based Review
5. Chronic Constipation: A Critical Review
6. Sexual Desire Disorders
7. Subclinical Hypothyroidism: Psychiatric Disorders and Symptoms
8. The Link between Thyroid Function and Depression


Written By: Steven F. Hotze, M.D.

Steven F. Hotze, M.D., is the founder and CEO of the Hotze Health & Wellness Center, Hotze Vitamins and Physicians Preference Pharmacy International, LLC.


Leave a Reply

Your email address will not be published. Required fields are marked *

Contact Us

"*" indicates required fields

By filling out the above, you agree to receive educational, informative emails on alternative medicine and hormone balancing. You will have the option to unsubscribe at any time.


AboutHotze Health & Wellness Center

Since 1989, Hotze Health & Wellness Center has helped over 33,000 patients get their lives back using bioidentical hormones that restore hormones to optimal levels, strengthen immune systems, and increase energy levels. Our treatment regimen addresses the root cause of hypothyroidism, adrenal fatigue, menopause, perimenopause, low testosterone, allergies, and candida.

Led by best-selling author, radio host and leading natural health expert, Steven F. Hotze, M.D., our medical team has over 100 years’ combined medical experience backed by a staff of nearly 100 caring professionals who provide an environment of hope and extraordinary hospitality for each of our patients, who we call our guests. It is our deepest desire to help you obtain and maintain health and wellness naturally so that you may enjoy a better quality of life, pure and simple.



Do you want to live a healthy, happy, purpose-driven life? Do you want to restore your health so that your loss of energy, weight gain, joint pain, depression and lack of drive or motivation won’t hold you back from achieving your personal and professional goals?

Dr. Steven Hotze wants that for you, too. In fact, in his powerful and passionate video entitled, “What I Believe”, Dr. Hotze shares how his Christian worldview and pivotal experiences have ignited a deep desire to offer the message of hope and optimal health to all who need to hear it.

Follow Us

As seen on:

  • ABC
  • Fow News Channel
  • NBC
  • CNN
  • The Biography Channel
  • Bloomberg Businessweek
  • The Early Show
  • Good Morning Texas
  • Great Day Houston

Our Doctors

At Hotze Health & Wellness Center, our doctors are changing the way women and men are treated through the use of bioidentical hormones. Our natural treatments have helped over 33,000 individuals with hypothyroidism, adrenal fatigue, menopause, perimenopause, low testosterone, allergies, candida, detoxification and nutritional deficiencies.

Meet our doctors

Guest Testimonials

Melanie B.

"I went from feeling tired and foggy to to getting my energy and vitality back!”

Read More guest testimonials
Pam White
Pam White
At Hotze Health and Wellness YOU can truly find restoration of your health and vibrant life! You will find the most caring and effective healthcare available! Don't hesitate call them today!!!
Ron Guidry
Ron Guidry
Doctors are not the final authority in our journey of achieving/maintaining health and wellness but having a good team of doctors in your support and guidance community is not only helpful it is wise and also essential. The team and staff at Hotze Health and Wellness are health professionals that you can trust to help you navigate all the misinformation that may be keeping you separated from your optimal level of health.
Caral Reeves
Caral Reeves
Hotze Beauty is a first class facility! Extreme level of professionalism , knowledge & genuine care❤️‍🩹
Julie Hryszko
Julie Hryszko
I’ve been a guest at this facility for 15 years. They are the most efficient, thorough and caring group of individuals I’ve ever experienced. Dr Hotze looks to change the way a typical doctor treats patients and looks for root causes to eliminate medical issues instead of treating “symptoms”. My life has improved 100% since my initial visit. The cost of the treatments are worth it.
Shavon Sisson
Shavon Sisson
Always a great experience dealing with everyone at Hotze Heath and Wellness! Everyone is kind and helpful.
Kori Misson
Kori Misson
I cannot accurately describe in words how I feel about this practice and the entire staff. I have had quite a few health issues throughout the years, rheumatoid arthritis, sjogrens, weight gain, hair loss, irritability, and that is just the beginning. I had pretty much given up on feeling good, just decided to "live with it" and hope for the best. Two very close friends love the Hotze Wellness Clinic and they have experienced life changing health. Made my appointment and from the beginning I felt heard. Not a in and out fast food style practice. They are looked and are looking at my entire body for overall health and wellness. Connections from mind and body to clinical blood work, even dental questions....they care and I feel as if I can trust them. I am on a path to complete wellness and my goal is to have my RA back in remission as it once was....make yourself a priority. Having hope is an incredible feeling!